If infusion rate-related reactions occur, stop the infusion and restart at a slower rate. ![]() ![]() Infuse IV slowly over at least 30 minutes. Storage: If reconstituted digoxin immune Fab is not used immediately, it may be stored under refrigeration at 2 to 8 degrees C (36 to 46 degrees F) for up to 4 hours. The reconstituted product may be diluted with 0.9% Sodium Chloride Injection to a convenient volume.įor patients receiving relatively small doses, the appropriate dose of the reconstituted solution may be withdrawn using a tuberculin syringe and then injected IV or diluted in 0.9% Sodium Chloride Injection and infused or injected IV.įor patients receiving doses less than 3 mg, dilute the reconstituted solution with 36 mL of 0.9% Sodium Chloride Injection to give a solution containing 1 mg/mL of digoxin immune Fab. The resulting solution should be clear, colorless, approximately isosmotic, and contain 10 mg/mL of digoxin immune Fab. Reconstitute by adding 4 mL of Sterile Water for Injection to the vial and gently mixing. Digoxin immune Fab is administered by intravenous infusion or bolus injection.Ĭlosely monitor the patient's temperature, blood pressure, electrocardiogram, and serum potassium concentration before and after digoxin immune Fab administration.
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